The fourth chronicle of Matthew Bartholomew continues the adventures of the 14th-century Cambridge physician when he is called to attend to two deaths from some poisoned wine. The opening of a new and very well-endowed college has created petty infighting amongst the academics as new appointments are made. The winter and spring have been appallingly wet, there is a fever outbreak amongst the poorer townspeople and the country is not yet fully recovered from the aftermath of the plague.

Hugh of Singleton, fourth son of a minor knight, has been educated as a clerk, usually a prelude to taking holy orders. However, feeling no certain calling despite a lively faith, he turns to the profession of surgeon, training in Paris and then hanging out his sign in Oxford. A local lord asks him to track the killer of a young woman whose bones have been found in the castle cesspit. She is identified as the impetuous missing daughter of a local blacksmith, and her young man, whom she had provoked very publicly, is in due course arrested and sentenced at the Oxford assizes.

Salisbury, 1226. A young pregnant woman is found tangled in reeds in the river Avon, her identity a mystery. Grieving widow Ela Longespée is determined to succeed her husband as sheriff of Salisbury, and quickly takes charge of the investigation. She soon finds herself in the thick of a neighborhood scandal and a struggle to maintain her authority. With multiple suspects, can she identify the true killer? 

In the sapping summer heat of 1665, there is little celebration in London of the naval victory at the Battle of Lowestoft. The King, his retinue and anyone with sufficient means has fled the plague-ridden city, its half-deserted streets echoing the sound of bells tolling the mounting number of deaths. Those who remain clutch doubtful potions to ward off the relentless disease and dart nervously past shuttered buildings, watchful for the thieves who risk their lives to plunder what has been left behind.

Oxford, Spring 1353. When young bookseller Nicholas Elyot discovers the body of student William Farringdon floating in the river Cherwell, it looks like a drowning. Soon, however, Nicholas finds evidence of murder. Who could have wanted to kill this promising student? As Nicholas and his scholar friend Jordain try to unravel what lies behind William's death, they learn that he was innocently caught up in a criminal plot.

The nominal king, Edward VI, is 11 years old. His uncle, Edward Seymour, Lord Hertford, rules as Edward's regent and Protector. In the kingdom, radical Protestants are driving the old religion into extinction, while the Protector's prolonged war with Scotland has led to hyperinflation and economic collapse. Rebellion is stirring among the peasantry. Matthew Shardlake has been working as a lawyer in the service of Henry's younger daughter, the lady Elizabeth. 

The Carolinas, 1699: The citizens of Fount Royal believe a witch has cursed their town with inexplicable tragedies -- and they demand that beautiful widow Rachel Howarth be tried and executed for witchcraft. Presiding over the trial is traveling magistrate Issac Woodward, aided by his astute young clerk, Matthew Corbett. Believing in Rachel's innocence, Matthew will soon confront the true evil at work in Fount Royal....

In medieval England, four children have been murdered, and the townsfolk blame their Jewish neighbors. The doctor chosen to investigate is a woman, Adelia. As she examines the victims and retraces their last steps, she must conceal her true identity in order to avoid accusations of witchcraft. Along the way, she's assisted by Sir Rowley Picot, a man with a personal stake in the investigation. A former Crusader knight, Rowley may be a needed friend - or the fiend for whom they are searching.

The Monastery at Whitby is ruled over by the powerful and independent Abbess Hild. But when she needs someone to confide in, she turns to the honest warmth of her friend Fridgyth, the half-pagan herb-wife. A divisive and life-altering decision taken at the Great Synod is swiftly overshadowed as the monastery is ravaged by a deadly plague. As she tends the sick, Fridgyth starts to suspect that not all the deaths are natural. Despite Hild's stern warnings "not to meddle" she sets out to investigate.

When the body of a young man is found stuffed into the tomb of a medieval knight, Parish Constable Daniel Haze is tasked with investigating his first solo murder case. Suspicion instantly falls on the only stranger to arrive in the village of Birch Hill just before the crime took place, but the American captain proves to be an unexpected asset. A former soldier and a skilled surgeon, Jason Redmond is not only willing to assist Haze with the investigation but will risk his own safety to apprehend the killer.

The much-feared and hated Eudo - the Lord Bishop of Winchester's clerk - is bludgeoned to death in Pershore Abbey and laid before the altar in the attitude of a penitent. Everyone who had contact with him had reason to dislike him, but who had reason to kill him? The Sheriff of Worcestershire's thief taker, wily Serjeant Catchpoll, and his new and unwanted superior, Undersheriff Hugh Bradecote, have to find the answer. And as the walls of the abbey close in on the suspects, the killer strikes again....

Ralph Delchard, a soldier who fought at the Battle of Hastings, and Gervase Bret, a talented lawyer, have been commissioned by William the Conqueror to look into irregularities brought to light during the compilation of the Domesday Book. A man’s body is found mutilated in Savernake Forest and the residents of Bedwyn sleep uneasy at night, fearing a monster stalking the town. When Ralph Delchard and Gervase Bret arrive, they discover that the locals are harbouring dark secrets and that the real killer may be a little closer to home....

London, September 1666. The Great Fire rages through the city, consuming everything in its path. Even the impregnable cathedral of St. Paul's is engulfed in flames and reduced to ruins. Among the crowds watching its destruction is James Marwood, son of a disgraced printer and reluctant government informer. In the aftermath of the fire, a semi-mummified body is discovered in the ashes of St. Paul's, in a tomb that should have been empty. The man's body has been mutilated, and his thumbs have been tied behind his back.

Gaius Petrius Ruso is a divorced and down-on-his-luck army doctor who has made the rash decision to seek his fortune in an inclement outpost of the Roman Empire, namely Britannia. After a 36-hour shift at the army hospital, he succumbs to a moment of weakness and rescues an injured slave girl, Tilla, from the hands of her abusive owner. And before he knows it, Ruso is caught in the middle of an investigation into the deaths of prostitutes working out of the local bar.

Cadfael's return to his Welsh homeland for a visit proves a rather discomfiting homecoming when an honorable nobleman turns up in a patch of forest with an arrow embedded in his chest. There are questions about the arrow, the man's daughter needs Cadfael's help, and a very odd burial takes place.

In 1350 the people of Cambridge are struggling to overcome the effects of the Black Death - and with a high mortality rate among priests and monks, the townsfolk are vulnerable to sinister cults that have sprung up. At Michaelhouse, Matthew Bartholomew is training new physicians when the body of a friar is found in the massive chest that the university uses to store precious documents. While investigating, Bartholomew stumbles across a derelict church being used as a meeting place for the mysterious sect he believes is at the heart of a web of blackmail.

The fourth chronicle of Matthew Bartholomew continues the adventures of the 14th-century Cambridge physician when he is called to attend to two deaths from some poisoned wine. The opening of a new and very well-endowed college has created petty infighting amongst the academics as new appointments are made. The winter and spring have been appallingly wet, there is a fever outbreak amongst the poorer townspeople and the country is not yet fully recovered from the aftermath of the plague.

Matthew Bartholomew, unorthodox but effective physician to Michaelhouse college in medieval Cambridge, is as worried as anyone about the pestilence that is ravaging Europe and seems to be approaching England. But he is distracted by the sudden and inexplicable death of the Master of Michaelhouse - a death the University authorities do not want investigated.

Matthew Bartholomew, doctor of medicine and fellow of Michaelhouse, Cambridge, is travelling with a party from the college to accept the gift of the living of a parish in Suffolk. One of his companions, Unwin, an unworldly scholar, is to be installed as priest. Their journey is not without incident - they are chased by footpads, pass through an eerie village abandoned after the recent plague and find a man barely alive on a gibbet - so they reach their destination with some relief. But their thoughts of recovering while enjoying the local Pentecostal Fair are soon curtailed.

Matthew Bartholomew jumps at the chance to travel to Ely with Brother Michael, as it will give him a unique opportunity to study in the richly stocked library of the Benedictine priory. Michael has been summoned to the city by his bishop, but it isn't until they arrive that they discover the reason - the bishop has been accused of murder. The charge seems ludicrous, but Michael takes the investigation seriously and energetically sets about his task. Almost immediately he discovers that there appears to have been a series of unexplained deaths in the area.

Believers in the theory of nominalism have set some Cambridge colleges at the throats of those who believe them to be heretics, and Michael, the senior proctor, has his work cut out to keep the peace. When a nominalist is murdered during a riot, Michael is certain he will easily find the killer amongst the Dominicans, but before he can get any sense out of them his junior proctor, Walcote, is found hanged, and he discovers that his trusted ally had arranged secret meetings at the St Ragelund Convent....

Cambridge, 1354. Christmas approaches, and the town is gripped by the worst blizzards in living memory. As the physician Matthew Bartholomew struggles to help the poorer citizens cope with freezing temperatures, his colleagues prepare for the festivities. The weather has trapped many travellers in the town, including Matthew's erstwhile love, Philippa. She and her wealthy husband are invited to Michaelhouse for the main feast, and Matthew is horrified that he does not immediately recognise the overweight, sulky woman who once stole his heart.

In Cambridge, 1355, the colleges of the fledgling university are as much at odds with each other as they are with the ordinary townfolk. This tension has recently been heightened by the return of two well-born murderers after receiving the King's pardon, showing no remorse but ready to confront those who helped convict them. And in the midst of this Bartholomew the physician is called to the local mill to examine two corpses. It is almost a relief to be able to turn his back on the fractious town, but as always in Cambridge nothing is disconnected.

In 1360, the Great Bridge over the River Cam is close to collapse. To repair it will cost the town and the University dear, especially if its rotten wood is replaced by more durable stone. As arguments rage over raising the money other, equally heated, differences are coming to the boil over the election of a new chancellor. While the majority support Brother Michael for the post, at least one of his opponents aims to seize it by fair means or foul. Then the discovery of a body under the bridge and the disappearance of two scholars throws a more sinister shadow over both disputes.

In the summer of 1358 the physician Matthew Bartholomew returns to Cambridge to learn that his beloved sister is in mourning after the unexpected death of her husband, Oswald Stanmore. Aware that his son has no interest in the cloth trade that made his fortune and reputation, Oswald has left the business to his widow, but a spate of burglaries in the town distracts Matthew from supporting Edith in her grief and attempting to keep the peace between her and her wayward son.