Georgia Brown’s profession as a urologist requires her to interact with plenty of naked men, but her romantic prospects have fizzled. The most important person in her life is her friend Jonah Tsukada, a funny, empathetic family medicine doctor who works at the same hospital in Charleston, South Carolina and who has become as close as family to her. Just after Georgia leaves the country for a medical conference, Jonah shares startling news. The hospital is instructing doctors to stop providing medical care for transgender patients.

Zadie Anson and Emma Colley have been best friends since their early 20s, when they first began navigating serious romantic relationships amid the intensity of medical school. Now they're happily married wives and mothers with successful careers - Zadie as a pediatric cardiologist and Emma as a trauma surgeon. Their lives in Charlotte, North Carolina are chaotic but fulfilling, until the return of a former colleague unearths a secret one of them has been harboring for years.

Diana O’Toole is perfectly on track. She will be married by 30, done having kids by 35, and move out to the New York City suburbs, all while climbing the professional ladder in the cutthroat art auction world. She’s an associate specialist at Sotheby’s now, but her boss has hinted at a promotion if she can close a deal with a high-profile client. She’s not engaged just yet, but she knows her boyfriend, Finn, a surgical resident, is about to propose on their romantic getaway to the Galápagos - days before her 30th birthday.

Ari Abrams has always been fascinated by the weather, and she loves almost everything about her job as a TV meteorologist. Her boss, legendary Seattle weatherwoman Torrance Hale, is too distracted by her tempestuous relationship with her ex-husband, the station’s news director, to give Ari the mentorship she wants. Ari, who runs on sunshine and optimism, is at her wits’ end. The only person who seems to understand how she feels is sweet but reserved sports reporter Russell Barringer.

A bookshop on the beach. A sizzling summer ahead. Join a new book club at the Seabreeze Inn. When sisters Ivy and Shelly Bay form a book club to help support a local bookshop on the beach, friends and guests of the old beach house inn are eager to join, although one new member harbors a potentially devastating secret. But when a threat arises during a book club meeting that could impact the entire beach community, members pull together, proving that the bonds of family and friendship are more important than ever in Summer Beach.

Lucky Armstrong is a tough, talented grifter who has just pulled off a million-dollar heist with her boyfriend, Cary. She’s ready to start a brand-new life, with a new identity - when things go sideways. Lucky finds herself alone for the first time, navigating the world without the help of either her father or her boyfriend, the two figures from whom she’s learned the art of the scam. When she discovers that a lottery ticket she bought on a whim is worth millions, her elation is tempered by one big problem: Cashing in the winning ticket means she’ll be arrested for her crimes.

Jade and Cam Lasky are by all accounts a happily married couple with two adorable kids, a spacious home, and a rapidly growing restaurant business. But their world is tipped upside down when Jade is confronted by a masked home invader. As Cam scrambles to gather the ransom money, Jade starts to wonder if they’re as financially secure as their lifestyle suggests, and what other secrets her husband is keeping from her.

Camille Gardener is a grieving - and angry - mother who, five years after her daughter’s death, is still obsessed with the privileged young man she believes to be responsible. When her rash actions draw the attention of a secret group of women - the collective - Camille is drawn into a dark web where these mothers share their wildly different stories of loss, as well as their desire for justice in a world where privilege denies accountability.

Frida Liu is struggling. She doesn’t have a career worthy of her Chinese immigrant parents’ sacrifices. She can’t persuade her husband, Gust, to give up his wellness-obsessed younger mistress. Only with Harriet, their cherubic daughter, does Frida finally attain the perfection expected of her. Harriet may be all she has, but she is just enough. Until Frida has a very bad day.

Jen and Riley have been best friends since kindergarten. As adults, they remain as close as sisters, though their lives have taken different directions. Jen married young, and after years of trying, is finally pregnant. Riley pursued her childhood dream of becoming a television journalist and is poised to become one of the first Black female anchors of the top news channel in their hometown of Philadelphia.

Dava Shastri, one of the world's wealthiest women, has always lived with her sterling reputation in mind. A brain cancer diagnosis at the age of 70, however, changes everything, and Dava decides to take her death - like all matters of her life - into her own hands. Summoning her four adult children to her private island, she discloses shocking news: In addition to having a terminal illness, she has arranged for the news of her death to break early, so she can read her obituaries.

Every December, Josie posts a letter from her home in London to the parents she lost on Christmas night many years ago. Each year, she writes the same three words: Missing you, always. But this year, her annual trip to the postbox is knocked off course by a bicycle collision with a handsome stranger - a stranger who will change the course of Josie's life.

Whether she’s playing an “age-defying” book editor on television or dazzling audiences on the Broadway stage, Sutton Foster manages to make it all look easy. How? Crafting. From the moment she picked up a cross stitch needle to escape the bullying chorus girls in her early performing days, she was hooked. Cross stitching led to crocheting, crocheting led to collages, which led to drawing, and so much more. Channeling her emotions into her creations centered Sutton as she navigated the significant moments in her life and gave her tangible reminders of her experiences.

Seventeen-year-old Lenni Pettersson lives on the Terminal Ward at the Glasgow Princess Royal Hospital. Though the teenager has been told she’s dying, she still has plenty of living to do. Joining the hospital’s arts and crafts class, she meets the magnificent Margot, an 83-year-old, purple-pajama-wearing, fruitcake-eating rebel, who transforms Lenni in ways she never imagined. As their friendship blooms, a world of stories opens for these unlikely companions who, between them, have been alive for one hundred years.

Sonya used to perform on stage. She used to attend glamorous parties, date handsome men, ride in fast cars. But somewhere along the way, the stage lights Sonya lived for dimmed for good. In their absence, came darkness — blackouts, empty cupboards, hazy nights she can't remember.