Lilian Girvan has been a single mother for three years - ever since her husband died in a car accident. One mental breakdown and some random suicidal thoughts later, she's just starting to get the hang of this widow thing. She can now get her two girls to school, show up to work, and watch TV like a pro. The only problem is she's becoming overwhelmed with being underwhelmed.

At any given moment in other people's houses, you can find...repressed hopes and dreams...moments of unexpected joy...someone making love on the floor to a man who is most definitely not her husband.... As the longtime local carpool mom, Frances Bloom is sometimes an unwilling witness to her neighbors' private lives. She knows her cousin is hiding her desire for another baby from her spouse, Bill Horton's wife is mysteriously missing, and now this....

The only child of a single mother, Nina has her life just as she wants it: a job in a bookstore, a kick-butt trivia team, a world-class planner and a cat named Phil. If she sometimes suspects there might be more to life than reading, she just shrugs and picks up a new book. When the father Nina never knew existed suddenly dies, leaving behind innumerable sisters, brothers, nieces, and nephews, Nina is horrified. They all live close by! They're all - or mostly all - excited to meet her! She'll have to Speak. To. Strangers. It's a disaster! 

Bridget and Will have the kind of relationship that people envy: They’re loving, compatible, and completely devoted to each other. The fact that they’re strictly friends seems to get lost on nearly everyone. For three decades, they’ve nurtured their baby, the Forsyth Trio - a chamber group they created as students with their Juilliard classmate Gavin Glantz. In the intervening years, Gavin has gone on to become one of the classical music world’s reigning stars, while Bridget and Will have learned to embrace the warm reviews and smaller venues that accompany modest success.

Julian Jessop, an eccentric, lonely artist and septuagenarian believes that most people aren’t really honest with each other. But what if they were? And so he writes - in a plain, green journal - the truth about his own life and leaves it in his local café. It’s run by the incredibly tidy and efficient Monica, who furtively adds her own entry and leaves the book in the wine bar across the street. Before long, the others who find the green notebook add the truths about their own deepest selves - and soon find each other In Real Life at Monica’s Café.

Lissie is a nurse in a gritty, hectic London neighborhood. Always terribly competent and good at keeping it all together, she’s been suffering quietly with PTSD after helping to save the victim of a shocking crime. Her supervisor quietly arranges for Lissie to spend a few months doing a much less demanding job in the little town of Kirrinfeif in Scottish Highlands, hoping that the change of scenery will help her heal. Lissie will be swapping places with Cormack, an Army veteran who’s Kirrinfeif’s easygoing nurse/paramedic/all-purpose medical man.

It wasn’t supposed to happen this way. When Eliza Hunt created the Hudson Valley Ladies’ Bulletin Board 15 years ago, she was happily entrenched in her picture-perfect suburban life with her husband and twin preschoolers. Now, with an empty nest and a crippling case of agoraphobia, the once-fun hobby has become her lifeline. So, when a rival parenting forum threatens the site’s existence, she doesn’t think twice before fabricating a salacious rumor to spark things up a bit. It doesn’t take long before that spark becomes a flame.

Cleo McDougal is a born politician. From congresswoman to senator, the magnetic, ambitious single mother now has her eye on the White House - always looking forward, never back. Until an estranged childhood friend shreds her in an op-ed hit piece gone viral. With seven words - "Cleo McDougal is not a good person" - the presidential hopeful has gone from in control to damage control, and not just in Washington but in life.

Celia Fairchild, known as advice columnist "Dear Calpurnia", has insight into everybody’s problems - except her own. Still bruised by the end of a marriage she thought was her last chance to create a family, Celia receives an unexpected answer to a “Dear Birthmother” letter. Celia throws herself into proving she’s a perfect adoptive mother material - with a stable home and income - only to lose her job. Her one option: sell the Charleston house left to her by her recently departed, estranged Aunt Calpurnia.

When overachiever Leena Cotton is ordered to take a two-month sabbatical after blowing a big presentation at work, she escapes to her grandmother Eileen's house for some long-overdue rest. Eileen is newly single and about to turn 80. She'd like a second chance at love, but her tiny Yorkshire village doesn't offer many eligible gentlemen. So they decide to try a two-month swap. But stepping into one another's shoes proves more difficult than either of them expected. Will swapping lives help Eileen and Leena find themselves...and maybe even find true love?

Poppy and Alex. Alex and Poppy. They have nothing in common. She’s a wild child; he wears khakis. She has insatiable wanderlust; he prefers to stay home with a book. And somehow, ever since a fateful car share home from college many years ago, they are the very best of friends. For most of the year they live far apart - she’s in New York City, and he’s in their small hometown - but every summer, for a decade, they have taken one glorious week of vacation together. 

When Vanessa Price quit her job to pursue her dream of traveling the globe, she wasn't expecting to gain millions of YouTube followers. Her mother and sister never saw the age of 30, and Vanessa doesn't want to take anything for granted. But after her half sister suddenly leaves Vanessa in custody of her baby daughter, life goes from "daily adventure" to "next-level bad" (now with bonus baby vomit in hair). The last person Vanessa expects to show up offering help is the hot lawyer next door, Adrian Copeland.

While her friends join the 'Wife Club' one by one, Poppy feels like that part of her life is done and dusted. Already married and divorced she's not desperate to go through all that again. But what if her divorce never actually went through? After a shock revelation Poppy not only discovers she is still married, but that Zac is about to have his second wedding!

Tiffy and Leon share an apartment. Tiffy and Leon have never met. After a bad breakup, Tiffy Moore needs a place to live. Fast. And cheap. But the apartments in her budget have her wondering if astonishingly colored mold on the walls counts as art. Desperation makes her open minded, so she answers an ad for a flatshare. Leon, a night shift worker, will take the apartment during the day, and Tiffy can have it nights and weekends. He'll only ever be there when she's at the office. In fact, they'll never even have to meet.

Isobel Johnson has spent her career in Liston Heights sidestepping the community’s high-powered families. But when she receives a threatening voicemail accusing her of anti-Americanism and a liberal agenda, she’s in the spotlight. Meanwhile, Julia Abbott, obsessed with the casting of the school’s winter musical, makes an error in judgment that has far-reaching consequences for her entire family.