Every catastrophe has a beginning. For the opioid crisis in America, the seed was a drug called OxyContin.

First hailed as a miracle drug for severe pain in the early 1990s, OxyContin went on to ignite a plague of addiction and death across America, fuelled by the aggressive marketing of its maker, Purdue Pharma, and the billionaire Sackler brothers who owned the company.

Investigative Journalist Barry Meier was the first to write about the elusive Sackler family, their role in this catastrophic epidemic and the army of local doctors, law enforcement and worried parents who tried to bring them down. We meet Lindsay Meyers, proud of being the youngest Oxy user she knows at just 16, local Doctor Art Van Zee who witnesses his community in the grip of a ferocious epidemic, the three billionaire Sackler brothers, and Laura Nagel, the government official who made it her mission to hold the company to account.

Equal parts crime thriller, medical detective story and business exposé, Pain Killer is the origin story of the opioid crisis, a hard-hitting look at how a supposed wonder drug became the trigger for a national tragedy.