Celeste Mason is the Pinterest stay-at-home supermom of other mothers’ nightmares. Despite her all-organic, SunButter-loving, free-range kids, her immaculate home, and her volunteering awards, she still has time to relax with a nice glass of pinot at the end of the day. The only thing that ruins it all is her workaholic, career-obsessed neighbor, who makes no secret of what she thinks of Celeste’s life choices every chance she gets.

Lily Stewart has reached a crossroads in her life. Her painting career hasn't taken off, her best friend has changed beyond recognition, and now she can't keep up with the rising cost of living in the city. With no one to turn to, Lily is forced to move from her apartment, but while packing she comes across a piece of mail that had slipped to the back of her junk drawer: a letter detailing further action needed to finalize the annulment of a quickie Vegas wedding. From 10 years ago! Lily decides it's time to gather up the pieces of her life.

Overworked and underappreciated, single mom Amy Byler needs a break. So when the guilt-ridden husband who abandoned her shows up and offers to take care of their kids for the summer, she accepts his offer and escapes rural Pennsylvania for New York City. Usually grounded and mild mannered, Amy finally lets her hair down in the city that never sleeps. She discovers a life filled with culture, sophistication, and - with a little encouragement from her friends - a few blind dates.

When Mackenzie, Sunna, and Maude move into a converted rental house, they are strangers with only one thing in common - important people in their lives have “ghosted” them. Mackenzie’s sister, Sunna’s best friend, and Maude’s fiancé - all gone with no explanation. So when a mangled, near-indecipherable letter arrives in their shared mailbox - hinting at long-awaited answers - each tenant assumes it’s for her. 

Everyone knows everyone in the tiny town of Bourne, but the Mitchell triplets are especially beloved. Mirabel is the smartest person anyone knows, and no one doubts it just because she can’t speak. Monday is the town’s purveyor of books now that the library’s closed - tell her the book you think you want, and she’ll pull the one you actually do from the microwave or her sock drawer. Mab’s job is hardest of all: get good grades, get into college, get out of Bourne.

Marnie MacGraw and Patrick Delaney have been in love for a few years now, enough to realize that they are imperfectly perfect together. Still, there are some things that maybe need a little attention. Marnie’s ebullient; he’s brooding. She thrives on change; he prefers stability. She sees marriage and parenthood in their future, but he can’t see beyond the shadow of an earlier tragedy. Then an eight-year-old surprise from Patrick’s past shows up on their doorstep, cartwheeling into their lives and spinning things in all directions. 

Cleo McDougal is a born politician. From congresswoman to senator, the magnetic, ambitious single mother now has her eye on the White House - always looking forward, never back. Until an estranged childhood friend shreds her in an op-ed hit piece gone viral. With seven words - "Cleo McDougal is not a good person" - the presidential hopeful has gone from in control to damage control, and not just in Washington but in life.

No new people: that's Annie Mercer's vow. It's bad enough that her boss sabotaged her chemistry career and her best friend tried to cure her with crystals. But after her fiancé, Jon, asks for space while he's gallivanting around Paris, Annie decides she needs space too - from everyone. Yet when Harper moves in next door, Annie can't help but train a watchful eye on the glamorous but fragile young woman. And if keeping Harper safe requires teaming up with Mo, a maddeningly optimistic amateur detective, who is she to mind her own business?

“You know what people really need? Somebody who will listen hard and then find a way to tell them, ‘It’s not all your fault. It’s going to work out fine. Don’t give up.’” So advice columnist ‘Dear Lily’ Brown deeply believes. But Lily could write a letter to herself, asking what to do about an ex-husband who still wants her dating advice, how to redecorate the family home she’s kept exactly the same since her parents died tragically young, how to move on with her strangely becalmed life...and what to do when your wild-child estranged sister storms back into town.

Very pregnant and not quite married, Jenny Harris doesn’t mind that she and her live-in fiancé, Dean, accidentally started their family a little earlier than planned. But Dean is acting distant, and the night he runs out for cigarettes and doesn’t come back, he demotes himself from future husband to sperm donor. And the very next day, Jenny goes into labor.

Isobel Johnson has spent her career in Liston Heights sidestepping the community’s high-powered families. But when she receives a threatening voicemail accusing her of anti-Americanism and a liberal agenda, she’s in the spotlight. Meanwhile, Julia Abbott, obsessed with the casting of the school’s winter musical, makes an error in judgment that has far-reaching consequences for her entire family.

Maggie, Eliza, and Tricia Sweeney grew up as a happy threesome in a seaside town in Connecticut. But after their mother’s death from cancer 15 years ago, the sisters drifted apart. Their one touchstone is their father, Bill Sweeney, a famous literary lion universally adored by critics, publishers, and book lovers. When Bill dies unexpectedly one cool June night, his shell-shocked daughters return to their childhood home. They aren’t quite sure what the future holds without their larger-than-life father, but they do know how to throw an Irish wake to honor a man of his stature.

Phronsie Linnelle was conceived at Woodstock in a serendipitous liaison between a free-spirited hippie and a farmer’s son and was born with magical wonder flickering in her DNA and rationality knit into her bones. All her life she’s been torn between the two. But now that she’s been betrayed by both love and the mother she once idolized, her rational side is winning. So when her best friend from childhood proposes that they give up on romance and marry each other, Phronsie agrees. 

February 4, 2003, promises to be a typical day for Olivia Ross - a greeting card writer whose passion project is a screenplay of her own. But after she and a handsome actor have a magical meet-cute in a coffee shop, they make a spontaneous pact: in 10 years, after they’ve found the success they’re just sure they’re going to achieve, they’ll return to the coffeehouse to partner up and make a film together. The only problem? Olivia neglected to get the stranger’s name. But she doesn’t forget his face - or the date.

At fifty-three, Maggie Harris has a good marriage and two mostly happy children. Perpetually anxious, she’s also accumulated a list of semi-reasonable fears: falling air conditioners, the IRS, identity theft, skydiving, and airbag recalls. But never once did Maggie worry that her husband of nearly thirty years would leave her.