Progressives claimed they knew how to solve homelessness, inequality, and crime. But in cities they control, progressives made those problems worse. 

At the age of 24, Jordan Barnes woke up next to a lifeless body, rifled through his dead friends’ pockets for any remaining heroin, and went right back to using. Strung out and homeless during the supposed best years of his life, there was no clear way out of the opioid crisis ravaging the streets of Portland, Oregon. But though Jordan had long accepted his fate, his parents still held out hope and would do everything in their power to get him the help he so desperately needed. 

While researching the toxic and addictive properties of sugar for Fat Chance, Robert Lustig made an alarming discovery - our pursuit of happiness is being subverted by a culture of addiction and depression from which we may never recover. Dopamine is the "reward" neurotransmitter that tells our brains we want more; yet every substance or behavior that releases dopamine in the extreme leads to addiction. Serotonin is the "contentment" neurotransmitter that tells our brains we don't need any more; yet its deficiency leads to depression.

Crystal methamphetamine is widely considered to be the most dangerous drug in the world, and nowhere is that more true than in the small towns of the American heartland. Methland tells the story of Oelwein, Iowa (pop. 6,159), which, like thousands of other small towns across the country, has been left in the dust by the consolidation of the agricultural industry, a depressed local economy, and an out-migration of people.

The opioid epidemic has been described as "one of the greatest mistakes of modern medicine." But calling it a mistake is a generous rewriting of the history of greed, corruption, and indifference that pushed the US into consuming more than 80 percent of the world's opioid painkillers. Journeying through lives and communities wrecked by the epidemic, Chris McGreal reveals not only how Big Pharma hooked Americans on powerfully addictive drugs but the corrupting of medicine and public institutions that let the opioid makers get away with it.

It is now 100 years since drugs were first banned in the United States. On the eve of this centenary, journalist Johann Hari set off on an epic three-year, 30,000-mile journey into the war on drugs. What he found is that more and more people all over the world have begun to recognize three startling truths: Drugs are not what we think they are. Addiction is not what we think it is. And the drug war has very different motives to the ones we have seen on our TV screens for so long.

When Dr. Will Cooke, an idealistic young physician just out of medical training, set up practice in the small rural community of Austin, Indiana, he had no idea that much of the town was being torn apart by poverty, addiction, and life-threatening illnesses. But he soon found himself at the crossroads of two unprecedented health-care disasters: a national opioid epidemic and the worst drug-fueled HIV outbreak ever seen in rural America. Confronted with Austin’s hidden secrets, Dr. Cooke decided he had to do something about them.

American Pain chronicles the rise and fall of this game-changing pill mill and how it helped tip the nation into its current opioid crisis. The narrative, which swings back and forth between Florida and Kentucky, is populated by a diverse cast of characters.

The Mexican drug trade has inspired prejudiced narratives of a war between north and south, White and Brown; between noble cops and vicious kingpins, corrupt politicians and powerful cartels. In this first comprehensive history of the trade, historian Benjamin T. Smith tells the real story of how and why this one-peaceful industry turned violent. He uncovers its origins and explains how this illicit business essentially built modern Mexico, affecting everything from agriculture to medicine to economics - and the country’s all-important relationship with the United States.

The prize-winning and best-selling author of Say Nothing presents a grand, devastating portrait of three generations of the Sackler family, famed for their philanthropy, whose fortune was built by Valium and whose reputation was destroyed by OxyContin. Empire of Pain is a masterpiece of narrative reporting and writing, exhaustively documented and ferociously compelling.

New hope for those suffering from conditions like depression, anxiety, bipolar disorder, addictions, PTSD, ADHD, and more. Though incidence of these conditions is skyrocketing, for the past four decades standard treatment hasn’t much changed, and success rates in treating them have barely improved, either. Meanwhile, the stigma of the “mental illness” label - damaging and devastating on its own - can often prevent sufferers from getting the help they need. Brain specialist and best-selling author Dr. Daniel Amen aims to change all that.

Equal parts crime thriller, medical detective story, and business exposé, Pain Killer takes a hard-hitting look at how a powerful drug touted as the salvation for millions triggered a national tragedy. At its inception, the legal narcotic OxyContin was seen as a pharmaceutical dream, a "wonder" drug that would herald a sea change in medical care while reaping vast profits for its maker. It did do that; but it also unleashed a public health crisis that cut a swath of despair and crime through unsuspecting small towns, suburbs, and cities across the country.

This book is about pleasure. It’s also about pain. Most important, it’s about how to find the delicate balance between the two, and why now more than ever finding balance is essential. We’re living in a time of unprecedented access to high-reward, high-dopamine stimuli: drugs, food, news, gambling, shopping, gaming, texting, sexting, Facebooking, Instagramming, YouTubing, tweeting....

Even after a decades-long opioid overdose crisis, intense controversy still rages over the fundamental nature of addiction and the best way to treat it. With uncommon empathy and erudition, Carl Erik Fisher draws on his own experience as a clinician, researcher, and alcoholic in recovery as he traces the history of a phenomenon that, centuries on, we hardly appear closer to understanding — let alone addressing effectively.

In this brilliant, heartbreaking book, Matthew Desmond takes us into the poorest neighborhoods of Milwaukee to tell the story of eight families on the edge. Arleen is a single mother trying to raise her two sons on the $20 a month she has left after paying for their rundown apartment. Scott is a gentle nurse consumed by a heroin addiction. Lamar, a man with no legs and a neighborhood full of boys to look after, tries to work his way out of debt. Vanetta participates in a botched stickup after her hours are cut.