Washington, DC, 2019: Laura Preston is a reclusive artist at odds with her older sister Beatrice as their elegant, formidable mother slowly slides into dementia. When a stranger contacts Laura claiming to be her brother who disappeared forty years earlier when the family lived in Bangkok, Laura ignores Bea’s warnings of a scam and flies to Thailand to see if it can be true. But meeting him in person leads to more questions than answers.

Anna Hart is a seasoned missing persons detective in San Francisco with far too much knowledge of the darkest side of human nature. When tragedy strikes her personal life, Anna, desperate and numb, flees to the Northern California village of Mendocino to grieve. She lived there as a child with her beloved foster parents, and now she believes it might be the only place left for her. Yet the day she arrives, she learns that a local teenage girl has gone missing.

Florence, the 1550s. Lucrezia, third daughter of the grand duke, is comfortable with her obscure place in the palazzo: free to wonder at its treasures, observe its clandestine workings, and to devote herself to her own artistic pursuits. But when her older sister dies on the eve of her wedding, Lucrezia is thrust into the limelight: the duke is quick to request her hand in marriage, and her father just as quick to accept on her behalf. Having barely left girlhood behind, Lucrezia must make her way in a court whose customs are opaque and where her arrival is not universally welcomed.

Twelve-year-old Bird Gardner lives a quiet existence with his loving but broken father, a former linguist who now shelves books in a university library. Bird knows to not ask too many questions, stand out too much, or stray too far. For a decade, their lives have been governed by laws written to preserve “American culture” in the wake of years of instability. To keep the peace and restore prosperity, the authorities relocate children of dissidents, especially those of Asian origin, and libraries are forced to remove books seen as unpatriotic—including the work of Bird’s mother.

Signal Fires opens on a summer night in 1985. Three teenagers have been drinking. One of them gets behind the wheel of a car, and, in an instant, everything on Division Street changes. Each of their lives, and that of Ben Wilf, a young doctor who arrives on the scene, is shattered. For the Wilf family, the circumstances of that fatal accident will become the deepest kind of secret, one so dangerous it can never be spoken. Dani Shapiro returns to the form that launched her career with a novel that examines the ties that bind families—and the secrets that can break them apart.

In June, 1954, eighteen-year-old Emmett Watson is driven home to Nebraska by the warden of the juvenile work farm where he has just served fifteen months for involuntary manslaughter. His mother long gone, his father recently deceased, and the family farm foreclosed upon by the bank, Emmett's intention is to pick up his eight-year-old brother, Billy, and head to California where they can start their lives anew. But when the warden drives away, Emmett discovers that two friends from the work farm have hidden themselves in the trunk of the warden's car.

Chemist Elizabeth Zott is not your average woman. In fact, Elizabeth Zott would be the first to point out that there is no such thing as an average woman. But it’s the early 1960s and her all-male team at Hastings Research Institute takes a very unscientific view of equality. Except for one: Calvin Evans; the lonely, brilliant, Nobel–prize nominated grudge-holder who falls in love with—of all things—her mind. True chemistry results. But like science, life is unpredictable.

Newlyweds Tricia and Ethan are searching for the house of their dreams. But when they visit the remote manor that once belonged to Dr. Adrienne Hale, a renowned psychiatrist who vanished without a trace four years earlier, a violent winter storm traps them at the estate… with no chance of escape until the blizzard comes to an end. In search of a book to keep her entertained until the snow abates, Tricia happens upon a secret room. One that contains audio transcripts from every single patient Dr. Hale has ever interviewed.

In misty, coastal Washington State, Isaac lives alone with his dog, grieving the recent death of his teenage son, Daniel. Next door, Lorrie, a working single mother, struggles with a heinous act committed by her own teenage son. Separated by only a silvery stretch of trees, the two parents are emotionally stranded, isolated by their great losses - until an unfamiliar 16-year-old girl shows up, bridges the gap, and changes everything.

After being rescued as infants from a sinking ocean liner in 1914, Marian and Jamie Graves are raised by their dissolute uncle in Missoula, Montana. There—after encountering a pair of barnstorming pilots passing through town in beat-up biplanes—Marian commences her lifelong love affair with flight. At fourteen she drops out of school and finds an unexpected and dangerous patron in a wealthy bootlegger who provides a plane and subsidizes her lessons, an arrangement that will haunt her for the rest of her life, even as it allows her to fulfill her destiny: circumnavigating the globe.

Everyone knows everyone in the tiny town of Bourne, but the Mitchell triplets are especially beloved. Mirabel is the smartest person anyone knows, and no one doubts it just because she can’t speak. Monday is the town’s purveyor of books now that the library’s closed - tell her the book you think you want, and she’ll pull the one you actually do from the microwave or her sock drawer. Mab’s job is hardest of all: get good grades, get into college, get out of Bourne.

Penobscot Indian Molly Ayer is close to "aging out" out of the foster care system. A community-service position helping an elderly woman clean out her home is the only thing keeping Molly out of juvie and worse.... As she helps Vivian sort through her possessions and memories, Molly learns that she and Vivian aren’t as different as they seem to be. A young Irish immigrant orphaned in New York City, Vivian was put on a train to the Midwest with hundreds of other children whose destinies would be determined by luck and chance.

On a bitter-cold day, in the December of his junior year at Harvard, Sam Masur exits a subway car and sees, amid the hordes of people waiting on the platform, Sadie Green. He calls her name. For a moment, she pretends she hasn’t heard him, but then, she turns, and a game begins: a legendary collaboration that will launch them to stardom. 

Seventeen-year-old Lenni Pettersson lives on the Terminal Ward at the Glasgow Princess Royal Hospital. Though the teenager has been told she’s dying, she still has plenty of living to do. Joining the hospital’s arts and crafts class, she meets the magnificent Margot, an 83-year-old, purple-pajama-wearing, fruitcake-eating rebel, who transforms Lenni in ways she never imagined. As their friendship blooms, a world of stories opens for these unlikely companions who, between them, have been alive for one hundred years.

Duchess Day Radley is a 13-year-old self-proclaimed outlaw. Rules are for other people. She is the fierce protector of her five-year-old brother, Robin, and the parent to her mother, Star, a single mom incapable of taking care of herself, let alone her two kids. Walk has never left the coastal California town where he and Star grew up. He may have become the chief of police, but he’s still trying to heal the old wound of having given the testimony that sent his best friend, Vincent King, to prison decades before. And he's in overdrive protecting Duchess and her brother. 

Truly Plaice, an overly large and ungainly girl, is the polar opposite of her sister, Serena Jane, the epitome of feminine perfection. With their parents dead, Truly and Serena Jane are separated: Serena Jane to live a life of privilege as the future May Queen and Truly to live on the outskirts of town, the subject of constant abuse and humiliation.

The world as we know it is ending. Evolution has reversed itself, affecting every living creature on earth. Science cannot stop the world from running backward, as woman after woman gives birth to infants that appear to be primitive species of humans. Thirty-two-year-old Cedar Hawk Songmaker, adopted daughter of a pair of big-hearted, open-minded Minneapolis liberals, is as disturbed and uncertain as the rest of America around her. But for Cedar, this change is profound and deeply personal. She is four months pregnant.

Written with astonishing clarity and evocative detail, convincing in its depiction of emotional pain, love, and vulnerability, 

Harvesting the Heart recalls the writing of Alice Hoffman and Sue Miller. Paige has only a few vivid memories of her mother, who left when she was five. Now, having left her father behind in Chicago for dreams of art school and marriage to an ambitious young doctor, she finds herself with a child of her own.

Greta Cahill never believed she would leave her village in the west of Ireland until she found herself on a ship bound for New York, along with her sister Johanna and a boy named Michael Ward. Labeled a "softheaded goose" by her family, Greta discovers that in America she can fall in love, raise her own family, and earn a living.

In 1919, Rachel Rabinowitz is a vivacious four-year-old living with her family in a crowded tenement on New York City's Lower East Side. When tragedy strikes, Rachel is separated from her brother, Sam, and sent to a Jewish orphanage where Dr. Mildred Solomon is conducting medical research. Subjected to X-ray treatments that leave her disfigured, Rachel suffers years of cruel harassment from the other orphans.

A debut of extraordinary distinction: through the trials of one unforgettable family, Ayana Mathis tells the story of the children of the Great Migration, a story of love and bitterness and the promise of a new America. In 1923, 15-year-old Hattie Shepherd flees Georgia and settles in Philadelphia, hoping for a chance at a better life. Instead, she marries a man who will bring her nothing but disappointment and watches helplessly as her firstborn twins succumb to an illness a few pennies could have prevented.

Rachel Stoltzfus never imagined she’d be the talk of her Old Order Mennonite community until whispers stir the moment her belly swells with new life. Unmarried and refusing to repent by naming the partner in her sin, Rachel feels the wrath of the religious sect as she is shunned by those she loves most and eventually forced to leave - driven out by her twin sister’s husband, the bishop. But secrets run deep in this cloistered community, and the bishop is hiding some of his own, threatening his conscience and his very soul.

Rabbit, Run is the book that established John Updike as one of the major American novelists of his - or any other - generation. Its hero is Harry “Rabbit” Angstrom, a onetime high-school basketball star who on an impulse deserts his wife and son. He is 26 years old, a man-child caught in a struggle between instinct and thought, self and society, sexual gratification and family duty - even, in a sense, human hard-heartedness, and divine Grace. Though his flight from home traces a zigzag of evasion, he holds to the faith that he is on the right path.

Graduate student Beth Winslow was sure she was ready to navigate the challenges of becoming a surrogate. But when early tests indicate possible abnormalities with the baby, Beth is unprepared for the parents' decision to end the pregnancy - and for the fierce love she feels for this unborn child. Desperate, she flees the city and seeks refuge at Hopen Haus, a home for unwed mothers deep in a Tennessee Mennonite community.

Clara Marsh is an undertaker who doesn't believe in God. She spends her solitary life among the dead, preparing their last baths and bidding them farewell with a bouquet from her own garden. Her carefully structured life shifts when she discovers a neglected little girl, Trecie, playing in the funeral parlor, desperate for a friend.

An ICU doctor in one of Seattle's most respected hospitals, Dr. Charlotte Reese is used to listening for the chop of the Medvac helicopter and preparing for the worst. But when a Jane hurtles through the doors of Beacon Hospital with tubes keeping her alive, Charlotte's stoic resolve begins to fail her and she becomes obsessed with unraveling the mystery of her patient's identity to solve what is looking more and more like an attempted murder.

Children Playing Before a Statue of Hercules is a collection of short stories, some classic, others impending, selected and introduced by David Sedaris.