For years, many have believed that the rise of superpowered mutants represents a threat to the survival of ordinary humans. The uncanny X-Men have dedicated their lives to proving that peaceful coexistence is possible. When a refugee spacecraft crashes on Earth, hounded by a warship bent on its destruction, the X-Men race to the rescue - only to learn that it carries beings of an entirely different order whose very existence may jeopardize life as we know it.

This gripping new anthology has over a dozen original tales starring the top-selling mutant heroes, the uncanny X-Men, dealing with their greatest foes, as well as the day-to-day trials of being mutants - trying to protect the world they've sworn to protect, a world that hates them for what they are! 

Piloting a shuttle through a deadly solar flare, Jean Grey saves the X-Men, but is possessed by one of the universe's most powerful forces - the Phoenix. As she adapts to her new powers, the mutant team launches an assault against the clandestine organization known as the Hellfire Club. Once inside, however, Jean is tricked by the villain Mastermind into betraying her teammates. She becomes first the Hellfire Club's Black Queen and then Dark Phoenix, as the power to destroy worlds bursts forth uncontrolled.

Marvel's most popular hero joins forces with Marvel's most popular super-team in this all-new trilogy. Spider-Man joins forces with the X-Men team when a mysterious photograph leads to a shocking discovery at the Time Displacement Core. The heroes must make a perilous journey into the past to prevent the destruction of the present.

Cyclops and Emma Frost re-form the team with the express purpose of "astonishing" the world. But when breaking news regarding the mutant gene unexpectedly hits the airwaves, will it derail their new plans before they even get started? As demand for the "mutant cure" reaches near-riot levels, the X-Men go head-to-head with the enigmatic Ord, with an unexpected ally - and some unexpected adversaries - tipping the scales!

Magneto, the X-Men's oldest, deadliest foe, has taken over a top-secret government installation that houses the Sentinels, powerful mutant-hunting robots. The X-Men must fight to keep this deadly technology out of Magneto's hands. But the Acolytes, Magneto's fanatical mutant followers, stand between the X-Men and victory - a victory that’s quickly slipping away - for a more ruthless enemy, the US government, holds the X-Men responsible for the installation's takeover!  

In a dark and dangerous future, the mutant-hunting machines known as the Sentinels rule America with an iron fist. Almost all mutants and superhumans have been exterminated. Only a handful of imprisoned mutants remain to fight against their oppressive robotic overseers! Now Kate Pryde, former X-Man, must travel back in time and warn her present-day teammates of the coming danger - and hopefully prevent this horrible future from ever taking place!

When Eddie Brock becomes biologically linked to a bizarre alien symbiote, the two share a common goal. At first, they seek to squash their arch-foe Spider-Man. But after repeated attempts, Venom reaches an uneasy truce with the web-spinner. Brock leaves New York and heads west to San Francisco, the city of his birth, eager to put trouble behind him, but trouble has different ideas. Brock commits himself to becoming a defender of the innocent, but he's a six-foot-three-inch, 260 lb. figure with bulging muscles and fangs like a shark. Venom quickly draws attention.

The fate of the entire Marvel Universe hangs in the balance as Earth's mightiest heroes face their greatest challenge! Summoned across the stars by the mysterious and unbelievably powerful Beyonder, the Avengers, Spider-Man, the Fantastic Four, and the X-Men are set against their deadliest foes on the mysterious planet known as Battleworld - with the winner promised the ultimate prize. But as battle lines are drawn, new alliances are forged, and old enemies clash, one among them is not willing to settle for anything less than godhood.

The Fantastic Four - the Thing, the Invisible Woman, the Human Torch, and Mr. Fantastic - have used their powers for the betterment of mankind. For years, the world's top scientists have dreamed of creating a quantum computer, a machine that would be infinitely more powerful than any based on the transistor. Now Reed Richards - Mr. Fantastic - has achieved that dream. He has birthed a device capable of creating the unbreakable cipher, predicting the weather, performing calculations, and retrieving knowledge at heretofore unimagined speeds.

Reed Richards is brought in on a consult to oversee a privately funded dimension-spanning device...a device that will give wealthy patrons the opportunity to experience interdimensional travel. Never mind that the consortium wants to launch a sweeping endeavor that would be branded as Fantastic Forays, with the world's greatest superhero team receiving a cut of the profits; their brilliant lead scientist, Rachel Hunt, has now discovered a way to safely traverse interspace - the main conduits situated between dimensions - that allows one access to a multitude of realities.  

Doctor Stephen Strange, the Sorcerer Supreme, has defeated demonic hordes, battled evil wizards, and tirelessly defended our realm against invading interdimensional armies. But when a dangerous dream begins inspiring normal people to act out their darkest ambitions, even Doctor Strange is pushed to his very limits.

Stark Enterprises has unleashed the Infinite Engine, which promises to be an energy source unlike anything ever seen before. But saboteurs from both A.I.M. and Hydra have set their sights on the engine as well - along with Dr. Doom. When a respected scientist is killed and the Engine taken over, Spiderman and Iron Man join forces to safeguard the Infinite Engine - and all of humanity. 

Under secret orders to assassinate the Widow, Hawkeye, the rough-edged marksman, finds himself caught up in a violent prison break that releases some of the world's most vicious and powerful criminals. Defying his superiors, Hawkeye joins forces with the sultry Russian spy and a mismatched group of personalities that include Spider-Man, Spider-Woman, Luke Cage, Captain America, and Iron Man. 

A previously unknown translation of an ancient grimoire, the Darkhold, has been unearthed by archaeologists in South America. But this chilling discovery will have far-reaching effects. Halfway across the globe, the Darkhold is relentlessly pursued by the Cabal of Scrier, an organization devoted to achieving ultimate power through whatever means necessary. And it is through their actions that a darkness from beyond the grave will return to haunt the Spectacular Spider-Man in the form of one of the most frightening and dangerous foes he's ever encountered....