Sometimes in medicine the only way to know what is truly going on in a patient is to operate, to look inside with one's own eyes. This audio is exploratory surgery on medicine itself, laying bare a science not in its idealized form, but as it actually is - complicated, perplexing, and profoundly human. Atul Gawande offers an unflinching view from the scalpel's edge, where science is ambiguous, information is limited, the stakes are high. In dramatic and revealing stories of patients and doctors, he explores how deadly mistakes occur and why good surgeons go bad.

Ruth Jefferson is a labor and delivery nurse at a Connecticut hospital with more than 20 years’ experience. During her shift, Ruth begins a routine checkup on a newborn, only to be told a few minutes later that she’s been reassigned to another patient. The parents are white supremacists and don’t want Ruth, who is African American, to touch their child. The hospital complies with their request, but the next day, the baby goes into cardiac distress while Ruth is alone in the nursery. Does she obey orders or does she intervene?  

Everything about 15-year-old Cat's new town in rural Michigan is lonely and off-kilter until she meets her neighbor, the manic, beautiful, pill-popping Marlena. Cat, inexperienced and desperate for connection, is quickly lured into Marlena's orbit by little more than an arched eyebrow and a shake of white-blond hair. As the two girls turn the untamed landscape of their desolate small town into a kind of playground, Cat catalogues a litany of firsts - first drink, first cigarette, first kiss - while Marlena's habits harden and calcify.

Ani FaNelli seems to have it all: a glamorous job at a glossy magazine, an enviable figure with the wardrobe to match, and a handsome fiancé from a distinguished blue-blood family. But Ani FaNelli is an invention, that veneer of perfection carefully assembled in an attempt to distance herself from a shocking, sordid past.

Luke Richardson has returned home after burying Natalie, his beloved wife of sixteen years, ready to face the hard job of raising their three children alone. But there's something he's not prepared for - a blue envelope with his name scrawled across the front in Natalie's handwriting, waiting for him on the floor of their suburban Michigan home.

Leah Thornton’s life, like her Southern Living home, has great curb appeal. But a paralyzing encounter with a can of frozen apple juice in the supermarket shatters the façade, forcing her to admit that all is not as it appears. When her best friend gets in Leah’s face about her refusal to deal with her life and her drinking, Leah is forced to make a decision. Can this brand-conscious socialite walk away from the country club into 28 days of rehab?

Two cousins, Rory and Arden, lie unconscious in a hospital burn unit. The fire, which broke out in their shared college dorm room, killed another student, and the police want answers. Tension between Rory and Arden's parents was already at an all-time high before the fire, owing to a recent financial crisis and the decline of the family business. As the parents huddle anxiously in the waiting room, carefully avoiding the subject of their own unraveling relationships, disturbing truths come to light.

From marriage, infidelity, and the mayhem of motherhood to scandal, tragedy, and illness - three women seek peace and comfort in Nantucket as they cope with life's challenges. Three women - burdened with small children, unwieldy straw hats, and some obvious emotional issues - tumble onto the Nantucket airport tarmac one hot June day. Vicki is trying to sort through the news that she has a serious illness. Her sister, Brenda, has just left her job after being caught in an affair with a student. And their friend Melanie, after seven failed in vitro attempts, is pregnant at last.

Megan Mazeros and Lauren Mabrey are complete opposites on paper. Megan is a girl from a modest Midwest background, and Lauren is the daughter of a senator from an esteemed New England family. But in 1999, Megan and Lauren become college roommates and, as two young women struggling to find their place on campus, they forge a strong, albeit unlikely, friendship. The two quickly become inseparable, sharing clothes, advice and their most intimate secrets.

Carolyn Mackler's Printz Honor book - starring the unforgettably funny, body-conscious Virginia Shreves - returns in this 15th anniversary edition featuring text updates and never-before-heard material from the author. Fifteen-year-old Virginia feels like a plus-sized black sheep in her family, especially next to her perfect big brother Byron. Not to mention her best friend has moved, leaving Virginia to navigate an awkward relationship with a boy alone. In order to survive, Virginia decides to follow a "Fat Girl Code of Conduct", which works, until the unthinkable causes her family's facade to crumble.

Ramona was only five years old when Hurricane Katrina changed her life forever. Since then it's been Ramona and her family against the world. Standing over six feet tall, with unmistakable blue hair, Ramona is sure of three things: She likes girls, she's fiercely devoted to her family, and she knows she's destined for something bigger than the trailer she calls home in Eulogy, Mississippi. But juggling multiple jobs, her flaky mom, and her well-meaning but ineffectual dad forces her to be the adult of the family.

Sammie McCoy is a girl with a plan: graduate at the top of her class and get out of her small town as soon as possible. Nothing will stand in her way - not even the rare genetic disorder the doctors say will slowly steal her memories and then her health. So the memory book is born: a journal written to Sammie's future self, so she can remember everything, from where she stashed her study guides to just how great it feels to have a best friend again.

Liz Murray was born to loving but drug-addicted parents in the Bronx. In school she was taunted for her dirty clothing and lice-infested hair, eventually skipping so many classes that she was put into a girls' home. At age 15, Liz found herself on the streets when her family finally unraveled. She learned to scrape by, foraging for food and riding subways all night to have a warm place to sleep. Then, when Liz's mother died of AIDS, she decided to take control of her own destiny.

For Penny Lee high school was a total nonevent. Her friends were okay, her grades were fine, and while she somehow managed to land a boyfriend, he doesn't actually know anything about her. When Penny heads to college in Austin, Texas, to learn how to become a writer, it's 79 miles and a zillion light-years away from everything she can't wait to leave behind.

The famed Internet personality - named one of Rolling Stone's Funniest People on Twitter and creator of the viral #notokay for women to share their stories of sexual assault - and best-selling author of Everything Is Perfect When You're a Liar turns her laser-like wit to anxiety, parenthood (or "the sheer insanity of being in charge of the safety and livelihood of three people besides myself"), popular culture, and more in this razor sharp essay collection.