Brian Timilty is running for mayor on an anti-superhero ticket, and the amazing Spider-Man is his biggest target. But Timilty is secretly the pawn of Tyler Stewart, a wealthy businessman seeking to take over New York's mobs. To ensure his success, Stewart hires two of Spider-Man's deadliest foes, Electro and the Rhino, and executes a plan guaranteed to keep the wall-crawler from interfering with his grand designs: He frames Spider-Man for a grisly murder! Forced into hiding, Spider-Man must find a way to clear his name without being shot on sight, for he is wanted dead or alive.

The fate of the entire Marvel Universe hangs in the balance as Earth's mightiest heroes face their greatest challenge! Summoned across the stars by the mysterious and unbelievably powerful Beyonder, the Avengers, Spider-Man, the Fantastic Four, and the X-Men are set against their deadliest foes on the mysterious planet known as Battleworld - with the winner promised the ultimate prize. But as battle lines are drawn, new alliances are forged, and old enemies clash, one among them is not willing to settle for anything less than godhood.

Beginning with a novella by Spider-Man's co-creator Stan Lee and veteran Marvel writer Peter David retelling the wall-crawler's origin, this exciting anthology has original stories featuring one of the world's most enduring heroes.

What drives the Man Without Fear? Matt Murdock was raised by a single father, an over-the-hill prizefighter with one last chance to make good - a chance that cost him his life. Taunted and tormented by other children, Matt's life was irrevocably altered after he was blinded by radioactive materials while saving the life of an old man. The payoff? An unbreakable will and a keen intelligence, helping focus the super-senses with which he was blessed during the accident. His story is one of love, pain, disappointment, and strength.

On several occasions, a half-dozen of Spider-Man's greatest enemies have banded together as the Sinister Six. Now, at the behest of a deadly benefactor known only as the Gentleman, the Chameleon has been tasked with assembling a new Sinister Six with the most ambitious scheme yet! Soon, he has recruited the Vulture, freed Electro and Dr. Octopus from prison, and been joined by the Gentleman's mysterious ward, Pity. That only leaves Mysterio, but the master of illusion has a plan of his own. 

Born to a rarified breed of Russian aristocracy, Kraven the Hunter had stalked and killed every animal known to man and considered himself the world's best big-game hunter. It was this confidence that brought him to New York years ago, in an obsessive quest to hunt what he considered the city's greatest prey: Spider-Man. But his target eluded him time and again, mocking him at every turn.   

No evildoers have tried to flatten Peter Parker in weeks. His marriage to Mary Jane is stronger than ever, and he's enjoying his job as a high-school science teacher. Life is good. Naturally, that doesn't last. When Peter learns that his old enemy, the Rhino, is on a rampage in Times Square, he suits up as Spider-Man to stop the destructive villain in his tracks. But he's unexpectedly foiled in his attempts by the Black Cat, a former ally and old flame. The Cat informs Peter that the Rhino is just a distraction - the real threat comes from a group of Ancients.

Peter Parker is caught in a complicated web. Working in a cutting-edge laboratory, he's a young scientist who's trying to make a difference. Yet he's constantly burdened by the responsibilities of his second career as the crime-fighting Spider-Man. Wilson Fisk - the so-called Kingpin of Crime - has returned to New York, establishing himself publicly as an altruistic entrepreneur and philanthropist. Spider-Man knows better, but he can't uncover Fisk's scheme, which, if executed, will make the crime lord too big to fail. 

A scientist finds a way to create perfect humans, heal the lame, and cure the sick. Dr. Aron Esterhazy's new formula can even turn ordinary people into superbeings. Everyone who finds out about it wants it - but who will control it?

J. Jonah Jameson, the publisher of the Daily Bugle, has denounced Spider-Man from the beginning, convincing New Yorkers to see him as a criminal and a menace. But when a robot attack on Manhattan injures Peter Parker's students and Jameson blames Spider-Man, their feud takes on a personal dimension. 

Two collections in a single volume featuring New York’s favorite spider super hero! Join forces with Spider-Man as he swings through a world of adventure with his super hero friends! Defeat the shape-shifting Lizard before he destroys Peter’s school, help the incredible Hulk take out the trash (as in bad guys!), battle the Sinister Six, get zapped by Electro, join in a Wild West Spidey rodeo, get starstruck with Rocket and Groot on Broadway, and much more!   

In a Manhattan warehouse, an innocent man has been murdered during a mysterious crime. Evidence points to the involvement of Venom - the alien symbiote obsessed with Spider-Man's destruction. Yet Venom has always safeguarded innocent lives. Has Venom gone completely around the bend, or is there another suspect? Spider-Man thinks there is more to the crime than meets the eye. The specter of the Hobgoblin, one of Spider-Man's nastiest foes, falls on a series of thefts and leads the web-slinger to a deadly secret that may cause New York's destruction. 

A previously unknown translation of an ancient grimoire, the Darkhold, has been unearthed by archaeologists in South America. But this chilling discovery will have far-reaching effects. Halfway across the globe, the Darkhold is relentlessly pursued by the Cabal of Scrier, an organization devoted to achieving ultimate power through whatever means necessary. And it is through their actions that a darkness from beyond the grave will return to haunt the Spectacular Spider-Man in the form of one of the most frightening and dangerous foes he's ever encountered.... 

When Eddie Brock becomes biologically linked to a bizarre alien symbiote, the two share a common goal. At first, they seek to squash their arch-foe Spider-Man. But after repeated attempts, Venom reaches an uneasy truce with the web-spinner. Brock leaves New York and heads west to San Francisco, the city of his birth, eager to put trouble behind him, but trouble has different ideas. Brock commits himself to becoming a defender of the innocent, but he's a six-foot-three-inch, 260 lb. figure with bulging muscles and fangs like a shark. Venom quickly draws attention.

Hoping to snag some rent-paying photos of his arachnid-like alter ego in action, Peter Parker goes looking for trouble - and finds it in the form of a mysterious, mythical stone tablet coveted by both the Kingpin and the Maggia. Caught in the crosshairs of New York's most nefarious villains, Peter also runs afoul of his friends - and the police! His girlfriend, Gwen Stacy, isn't too happy with him either. And the past comes back to haunt him when the Maggia's assumed-dead leader resurfaces in pursuit of the troublesome tablet.