The Avengers journey into deep space, where they unite the intergalactic races against the Builders - deadly aliens who seek to destroy the known galaxy. While the heroes are gone, Thanos sets his sights on Earth, sending the Black Order to launch the assault. It falls to the other heroes of Earth - the Inhumans, the Black Panther, Namor the Sub-Mariner, Doctor Strange, the X-Men, and more - to defend Attilan, Wakanda, Atlantis, and the rest of the planet. To defeat Thanos, the defending forces will need to deploy a new weapon - one that may be as deadly as the invading force. 

In a dark and dangerous future, the mutant-hunting machines known as the Sentinels rule America with an iron fist. Almost all mutants and superhumans have been exterminated. Only a handful of imprisoned mutants remain to fight against their oppressive robotic overseers! Now Kate Pryde, former X-Man, must travel back in time and warn her present-day teammates of the coming danger - and hopefully prevent this horrible future from ever taking place!

Iron Man and Captain America are two core members of the Avengers, the world's greatest superhero team. But when a tragic battle blows a hole in the city of Stamford, killing hundreds of people, the US government demands that all superheroes unmask and register their powers. To Tony Stark - Iron Man - it's a regrettable but necessary step. To Captain America, it's an unbearable assault on civil liberties. 

Magneto, the X-Men's oldest, deadliest foe, has taken over a top-secret government installation that houses the Sentinels, powerful mutant-hunting robots. The X-Men must fight to keep this deadly technology out of Magneto's hands. But the Acolytes, Magneto's fanatical mutant followers, stand between the X-Men and victory - a victory that’s quickly slipping away - for a more ruthless enemy, the US government, holds the X-Men responsible for the installation's takeover!  

The fate of the entire Marvel Universe hangs in the balance as Earth's mightiest heroes face their greatest challenge! Summoned across the stars by the mysterious and unbelievably powerful Beyonder, the Avengers, Spider-Man, the Fantastic Four, and the X-Men are set against their deadliest foes on the mysterious planet known as Battleworld - with the winner promised the ultimate prize. But as battle lines are drawn, new alliances are forged, and old enemies clash, one among them is not willing to settle for anything less than godhood.

T'Challa faces the gods of his parents. Vampires stalk Shuri and a Dora Milaje in voodoo-laced New Orleans. Erik Killmonger grapples with racism, Russian spies, and his own origins. Here are 18 brand-new tales of Wakanda, its people, and its legacy. 

Under secret orders to assassinate the Widow, Hawkeye, the rough-edged marksman, finds himself caught up in a violent prison break that releases some of the world's most vicious and powerful criminals. Defying his superiors, Hawkeye joins forces with the sultry Russian spy and a mismatched group of personalities that include Spider-Man, Spider-Woman, Luke Cage, Captain America, and Iron Man. 

Born to a rarified breed of Russian aristocracy, Kraven the Hunter had stalked and killed every animal known to man and considered himself the world's best big-game hunter. It was this confidence that brought him to New York years ago, in an obsessive quest to hunt what he considered the city's greatest prey: Spider-Man. But his target eluded him time and again, mocking him at every turn.   

This exciting new anthology has over a dozen original tales starring the vicious foes of Marvel's superheroes: Greg Cox's chronicle of the Super-Skrull's conflict with the Avengers, Michael Jan Friendman's story of evil Loki's latest attempt to snare his stepbrother Thor, Adam-Troy Castro's tale of a mutant who brings Magneto and X-Men's Professor X together in a unique manner, Glenn Greenberg's pairing of Venom and the Absorbing Man in an unlikely jailbreak. 

Doctor Stephen Strange, the Sorcerer Supreme, has defeated demonic hordes, battled evil wizards, and tirelessly defended our realm against invading interdimensional armies. But when a dangerous dream begins inspiring normal people to act out their darkest ambitions, even Doctor Strange is pushed to his very limits.

Wolverine. Sabretooth. Silver Fox. Wraith. Maverick. Together, they were Team X, the best covert-ops team NATO had to offer. But a mission to retrieve a disk from a pair of Soviet agents proved to be more trouble than they bargained for. A Soviet operative codenamed the Black Widow, a mutant Interpol Officer named Sean Cassidy, and shape-changing freelance spy Mystique were also all after the disk. 

Cyclops and Emma Frost re-form the team with the express purpose of "astonishing" the world. But when breaking news regarding the mutant gene unexpectedly hits the airwaves, will it derail their new plans before they even get started? As demand for the "mutant cure" reaches near-riot levels, the X-Men go head-to-head with the enigmatic Ord, with an unexpected ally - and some unexpected adversaries - tipping the scales!

Thanos' pursuit of the Infinity Gems has always defined him. But when the Marvel heroes defeat him once again, Thanos' beloved Mistress Death grants him one final chance. Stripped of his powers and his old skin, Thanos embarks on a cosmic walkabout to reassert his power over himself and the Multiverse. Haunted by family - or the semblances of it - the Mad Titan may become something else entirely.

On several occasions, a half-dozen of Spider-Man's greatest enemies have banded together as the Sinister Six. Now, at the behest of a deadly benefactor known only as the Gentleman, the Chameleon has been tasked with assembling a new Sinister Six with the most ambitious scheme yet! Soon, he has recruited the Vulture, freed Electro and Dr. Octopus from prison, and been joined by the Gentleman's mysterious ward, Pity. That only leaves Mysterio, but the master of illusion has a plan of his own. 

Hydra has a synthetic pathogen that will make the entire human race dependent on them for the cure. A.I.M.'s newly developed nanotech compound to enslave humanity is dangerously close to contaminating the world's water supplies. Ultron is poised on the edge of Singularity, Earth's technology at his metallic fingertips. Dormammu has a plan to save the world - by claiming it as his own. The High Evolutionary is rewriting the human genome in a bid to turn humankind into a eugenic slave-race. Everybody wants to rule the world - and only the isolated Avengers can stop them.